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One or more keywords matched the following properties of Novembre, John
PropertyValue
keywords Computational Biology
keywords Computational Statistics
overview The Novembre research group uses computational tools to study genetic diversity in natural populations. Our goal is to develop widely used statistical methods for intelligently extracting information from large-scale genomic data with the aim to improve understanding of: (1) basic genomic biology, (2) the biology of heritable disease traits, (3) the genetic basis of evolutionary processes, and (4) the history and evolution of various species, especially humans. From a disciplinary perspective, most of the ideas we use are from theoretical population genetics, statistical genetics, and computational statistics. Much of our work is invigorated by addressing data from emerging genotyping and sequencing technologies applied to large or particularly interesting population samples.
One or more keywords matched the following items that are connected to Novembre, John
Item TypeName
Concept Models, Genetic
Concept Models, Theoretical
Concept Models, Statistical
Academic Article Accounting for background nucleotide composition when measuring codon usage bias.
Academic Article Fast model-based estimation of ancestry in unrelated individuals.
Academic Article The geographic spread of the CCR5 Delta32 HIV-resistance allele.
Academic Article Principal component analysis under population genetic models of range expansion and admixture.
Academic Article Characterizing bias in population genetic inferences from low-coverage sequencing data.
Academic Article Novel statistical methods for integrating genetic and stable isotope data to infer individual-level migratory connectivity.
Academic Article Power analysis of artificial selection experiments using efficient whole genome simulation of quantitative traits.
Academic Article Visualizing spatial population structure with estimated effective migration surfaces.
Academic Article Conflation of Short Identity-by-Descent Segments Bias Their Inferred Length Distribution.
Academic Article Using pseudoalignment and base quality to accurately quantify microbial community composition.
Academic Article Estimating Time to the Common Ancestor for a Beneficial Allele.
Academic Article Inference and visualization of DNA damage patterns using a grade of membership model.
Academic Article Exploring Population Structure with Admixture Models and Principal Component Analysis.
Academic Article Genetic history from the Middle Neolithic to present on the Mediterranean island of Sardinia.
Academic Article Fast and flexible estimation of effective migration surfaces.
Academic Article Haplotype-based inference of the distribution of fitness effects.
Academic Article Modeling the spatiotemporal spread of beneficial alleles using ancient genomes.
Academic Article Population genetic models for the spatial spread of adaptive variants: A review in light of SARS-CoV-2 evolution.
Grant Extending Tools for Visualization of Geographic Structure in Population Genomic Data
Grant Population Genetic Consequences of Recent Explosive Population Growth in Humans
Grant Haplotype-based analysis methods for population genomics
Search Criteria
  • Computational
  • modeling